General Englishinformalcolloquial
- To lose one's temper; to become extremely angry or enraged.
General Englishinformal
- To become emotionally overwhelmed or to break down, often resulting in crying, panic, or an inability to function normally.
General Englishneutral
- To misplace or cease to possess something, such as an object, a job, or an opportunity.
General Englishinformalpejorative
- To lose control of one's mental faculties; to become irrational or mentally unstable.