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1.
General English
informal
colloquial
At the limit of one's patience or endurance; extremely fed up or exasperated.
2.
General English
neutral
Reaching a specified level or point on the body or an object; as high as the indicated point.
3.
General English
informal
Filled, occupied, or overwhelmed to a large degree by something (for example, with work, money, problems, or other matters).
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