British EnglishAmerican EnglishGeneralinformalcolloquialdefensive
A confrontational or dismissive retort asking what consequence or importance should be attached to a statement; equivalent to 'So what?'.
2.
British EnglishAmerican EnglishGeneralneutralformal
A request for clarification about the relevance or implications of a previously mentioned fact or document; 'what of it' meaning 'what does that signify or lead to?'.